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Thursday, December 04, 2008

Erik is out of the hospital. He has been home for a few days. He was not responding to the treatments so the made a change and added Cyclophosamide (Cytoxan). I like knowing the real name because I know the chemistry and it gives me a visual in my head. The amide group is the most potent part of it. It contains O double bonded to C with N-H off of it. The main concern is with Erik's IGG levels. The problem in myeloma it effects the attachment of the immunoglobulin. The immunoglubulin is made up of 2 light chains and 2 heavy the coordination of the two is lost and the unattached light chain enters the blood and is excreted through the urine. These chains can cause injury to the kidneys, which is why he has to keep returning to the hospital for plasmaphoresis. We pray that his levels will decrease with the Cytoxan. The doctors told Erik it is the killer, which is evident when it is related to nitrogen mustard (gas).

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